miRNA description for miR-221-3p
miRNA accession	miR-221-3p
Species	Homo sapiens
miR-221-3p identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells [Extracellular vesicles]	34596354
Monocytic leukemia cells [Exosomes]	34388111
Monocytic leukemia cells [Exosomes]	34388111
Monocytic leukemia cells [Exosomes]	34388111
Monocytic leukemia cells [Exosomes]	34388111
Monocytic leukemia cells [Exosomes]	34388111
Pulmonary artery endothelial cells [Exosomes]	32132543
Pulmonary artery endothelial cells [Exosomes]	32132543
Urine [Exosomes]	24352158
Experiment description of studies that identified miR-221-3p in exosomes
1 Experiment ID 3202 Identified molecule miRNA Identification method Small RNA sequencing PubMed ID 34596354    Organism Homo sapiens Experiment description Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Authors Lee KS, Lee J, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS, Cho YW, Jo DG. Journal name J Extracell Vesicles Publication year 2021 Sample Mesenchymal stem cells Sample name Adipose tissue-derived stem cells Molecules identified in the study Protein miRNA Methods used in the study Flow cytometry Small RNA sequencing ddPCR EV-TRACK -
2 Experiment ID 2486 Identified molecule miRNA Identification method qRT-PCR PubMed ID 34388111    Organism Homo sapiens Experiment description miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Authors Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, Chen L. Journal name Aging Publication year 2021 Sample Monocytic leukemia cells Sample name THP1 Molecules identified in the study Protein miRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
3 Experiment ID 2487 Identified molecule miRNA Identification method qRT-PCR PubMed ID 34388111    Organism Homo sapiens Experiment description miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Authors Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, Chen L. Journal name Aging Publication year 2021 Sample Monocytic leukemia cells Sample name THP1 Molecules identified in the study Protein miRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
4 Experiment ID 2488 Identified molecule miRNA Identification method qRT-PCR PubMed ID 34388111    Organism Homo sapiens Experiment description miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Authors Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, Chen L. Journal name Aging Publication year 2021 Sample Monocytic leukemia cells Sample name THP1 Molecules identified in the study Protein miRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
5 Experiment ID 2489 Identified molecule miRNA Identification method qRT-PCR PubMed ID 34388111    Organism Homo sapiens Experiment description miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Authors Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, Chen L. Journal name Aging Publication year 2021 Sample Monocytic leukemia cells Sample name THP1 Molecules identified in the study Protein miRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
6 Experiment ID 2490 Identified molecule miRNA Identification method qRT-PCR PubMed ID 34388111    Organism Homo sapiens Experiment description miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Authors Liu W, Long Q, Zhang W, Zeng D, Hu B, Liu S, Chen L. Journal name Aging Publication year 2021 Sample Monocytic leukemia cells Sample name THP1 Molecules identified in the study Protein miRNA Methods used in the study Western blotting qRT-PCR EV-TRACK -
7 Experiment ID 1468 Identified molecule miRNA Identification method RT-PCR PubMed ID 32132543    Organism Homo sapiens Experiment description Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Authors Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B. Journal name Nat Commun Publication year 2020 Sample Pulmonary artery endothelial cells Sample name HPAEC Molecules identified in the study miRNA Methods used in the study RT-PCR EV-TRACK -
8 Experiment ID 1469 Identified molecule miRNA Identification method RT-PCR PubMed ID 32132543    Organism Homo sapiens Experiment description Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Authors Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B. Journal name Nat Commun Publication year 2020 Sample Pulmonary artery endothelial cells Sample name HPAEC Molecules identified in the study miRNA Methods used in the study RT-PCR EV-TRACK -
9 Experiment ID 357 Identified molecule miRNA Identification method RNA deep sequencing PubMed ID 24352158    Organism Homo sapiens Experiment description Characterization and deep sequencing analysis of exosomal miRNA in human urine Authors Lesley Cheng, Xin Sun, Bradley M. Coleman, Andrew F. Hill Journal name Kidney Int Publication year 2014 Sample Urine Sample name Urine - Normal Molecules identified in the study miRNA Methods used in the study RNA deep sequencing EV-TRACK EV140147: EV-METRIC:44%, 0%, 22%